Coxsackie is a town in Greene County, New York, United States. The population was 8,918 at the 2010 census. The name of the town is said to be derived from a Native American term, but it has various translations.Within the area governed as a town, there is also a village called Coxsackie. The town is in the northeast part of the county.The town of Coxsackie is notable for being the namesake of the Coxsackievirus, which was first isolated in this town.